Archer™ VARIANTPlex™ HRD Module

Flexible, efficient HRD assessment

Efficiently assess homologous recombination deficiency status in solid tumor samples with this HRD module designed to function as a standalone assay or as a spike-in with VARIANTPlex NGS panels.

Detect confidently with Archer VARIANTPlex NGS Panels for DNA.

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Learn how the VARIANTPlex HRD Module can identify key genomic alterations for your research.

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Product details

Module specifications

Specifications
Targeted genes-
Genomic alterationsHRD
Input nucleic acid required*10 ng
Recommended number of reads12 M
Hands-on time< 3.5 hours
Total library prep time1.5 days
Platform compatibilityIllumina®
Reagent formatLyophilized or liquid
Supported sample typesFFPE, fresh froze, cytology smear, FNA

*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50 ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200 ng is recommended.

The VARIANTPlex HRD module can be integrated into VARIANTPlex NGS assay as a spike-in or ran as a standalone assay.

Interested in adding this module to your panel?

Customize this NGS module by adding any of our functionally-tested designs or create a new panel that fits your exact requirements with Assay Marketplace.

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Benefits

  • Flexible, customizable insights—Combine pre-designed panels, create custom panel content, and easily add targets to your existing assay, while maintaining high performance with minimal workflow disruption.
  • Detect confidently—Anchored Multiplex PCR (AMP™) chemistry and Archer Analysis (version 7.4) uses allele‑specific copy number (ASCN) and indel information to generate a reliable HRD assessment score.
  • Achieve efficiency—Streamlined workflows for your lab are enabled by a choice of reaction-sized lyophilized reagents or high-throughput liquid reagents, while parallel workflows across all Archer panels provide efficient genomic characterization.

Ready to start?

Talk with our technical sales team. Learn how the VARIANTPlex HRD Module can assess HRD in your research.

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Frequently asked questions

Related products

References

RUO24-3031_001